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Incidence of treated first episode psychosis from an Australian early intervention service and its association with neighbourhood characteristics.

Identifieur interne : 000887 ( Main/Exploration ); précédent : 000886; suivant : 000888

Incidence of treated first episode psychosis from an Australian early intervention service and its association with neighbourhood characteristics.

Auteurs : Scott Eaton [Australie] ; Benjamin Harrap [Australie] ; Linglee Downey [Australie] ; Kristen Thien [Australie] ; Meghan Bowtell [Australie] ; Melissa Bardell-Williams [Australie] ; Aswin Ratheesh [Australie] ; Patrick Mcgorry [Australie] ; Brian O'Donoghue [Australie]

Source :

RBID : pubmed:31130401

Descripteurs français

English descriptors

Abstract

OBJECTIVES

Psychotic disorder incidence varies geographically and is associated with neighbourhood characteristics, including social deprivation, population density, unemployment, social capital or social fragmentation. Yet it is not known whether these findings are applicable to Australia's unique geography. This study aimed to determine whether the incidence of first episode psychosis (FEP) varies according to neighbourhood characteristics in an Australian cohort.

METHOD

This study included all young people, aged 15 to 24, with an FEP who attended Orygen Youth Health in Melbourne, from a geographically defined catchment area encompassing Northern and Western Melbourne, over a 44-month period. Neighbourhood demographic data was collected from the 2011 Australian National Census. Negative binomial regression was used to determine incidence rate ratios controlled for age, sex and migrant status.

RESULTS

A total of 747 young people had an FEP during the 44-month study period and 722 were included in this study. Of these, 58.0% were males and 67.9% had a non-affective psychotic disorder; the mean age of the cohort was 19.1 years. The incidence of FEP in young people aged 15 to 24 in the catchment area was 123.2 per 100,000 person-years. There was a higher incidence of FEP in neighbourhoods of greatest social deprivation (IRR = 1.65, CI = 1.06-2.51, p = .02), highest unemployment (IRR = 1.56, CI = 1.04-2.35, p = .03) and above average social fragmentation (IRR = 1.42, CI = 1.02-1.97, p = .04), when controlled for age, sex and migrant status.

CONCLUSIONS

This study highlights variation in psychotic disorder incidence and the need for this disparity to be reflected in appropriate resource allocation.


DOI: 10.1016/j.schres.2019.04.017
PubMed: 31130401


Affiliations:


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Le document en format XML

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<title level="j">Schizophrenia research</title>
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<term>Adolescent (MeSH)</term>
<term>Adult (MeSH)</term>
<term>Australia (epidemiology)</term>
<term>Catchment Area, Health (MeSH)</term>
<term>Early Medical Intervention (statistics & numerical data)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Incidence (MeSH)</term>
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<term>Humains (MeSH)</term>
<term>Incidence (MeSH)</term>
<term>Intervention médicale précoce (statistiques et données numériques)</term>
<term>Jeune adulte (MeSH)</term>
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<term>Troubles psychotiques (thérapie)</term>
<term>Troubles psychotiques (épidémiologie)</term>
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<term>Australia</term>
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<term>Psychotic Disorders</term>
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<term>Early Medical Intervention</term>
<term>Residence Characteristics</term>
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<term>Caractéristiques de l'habitat</term>
<term>Intervention médicale précoce</term>
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<term>Psychotic Disorders</term>
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<term>Australie</term>
<term>Troubles psychotiques</term>
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<term>Adolescent</term>
<term>Adult</term>
<term>Catchment Area, Health</term>
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<term>Humans</term>
<term>Incidence</term>
<term>Male</term>
<term>Socioeconomic Factors</term>
<term>Young Adult</term>
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<term>Adolescent</term>
<term>Adulte</term>
<term>Facteurs socioéconomiques</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Jeune adulte</term>
<term>Mâle</term>
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<front>
<div type="abstract" xml:lang="en">
<p>
<b>OBJECTIVES</b>
</p>
<p>Psychotic disorder incidence varies geographically and is associated with neighbourhood characteristics, including social deprivation, population density, unemployment, social capital or social fragmentation. Yet it is not known whether these findings are applicable to Australia's unique geography. This study aimed to determine whether the incidence of first episode psychosis (FEP) varies according to neighbourhood characteristics in an Australian cohort.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHOD</b>
</p>
<p>This study included all young people, aged 15 to 24, with an FEP who attended Orygen Youth Health in Melbourne, from a geographically defined catchment area encompassing Northern and Western Melbourne, over a 44-month period. Neighbourhood demographic data was collected from the 2011 Australian National Census. Negative binomial regression was used to determine incidence rate ratios controlled for age, sex and migrant status.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>A total of 747 young people had an FEP during the 44-month study period and 722 were included in this study. Of these, 58.0% were males and 67.9% had a non-affective psychotic disorder; the mean age of the cohort was 19.1 years. The incidence of FEP in young people aged 15 to 24 in the catchment area was 123.2 per 100,000 person-years. There was a higher incidence of FEP in neighbourhoods of greatest social deprivation (IRR = 1.65, CI = 1.06-2.51, p = .02), highest unemployment (IRR = 1.56, CI = 1.04-2.35, p = .03) and above average social fragmentation (IRR = 1.42, CI = 1.02-1.97, p = .04), when controlled for age, sex and migrant status.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSIONS</b>
</p>
<p>This study highlights variation in psychotic disorder incidence and the need for this disparity to be reflected in appropriate resource allocation.</p>
</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">31130401</PMID>
<DateCompleted>
<Year>2020</Year>
<Month>08</Month>
<Day>28</Day>
</DateCompleted>
<DateRevised>
<Year>2020</Year>
<Month>08</Month>
<Day>28</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1573-2509</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>209</Volume>
<PubDate>
<Year>2019</Year>
<Month>07</Month>
</PubDate>
</JournalIssue>
<Title>Schizophrenia research</Title>
<ISOAbbreviation>Schizophr Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Incidence of treated first episode psychosis from an Australian early intervention service and its association with neighbourhood characteristics.</ArticleTitle>
<Pagination>
<MedlinePgn>206-211</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0920-9964(19)30142-2</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.schres.2019.04.017</ELocationID>
<Abstract>
<AbstractText Label="OBJECTIVES">Psychotic disorder incidence varies geographically and is associated with neighbourhood characteristics, including social deprivation, population density, unemployment, social capital or social fragmentation. Yet it is not known whether these findings are applicable to Australia's unique geography. This study aimed to determine whether the incidence of first episode psychosis (FEP) varies according to neighbourhood characteristics in an Australian cohort.</AbstractText>
<AbstractText Label="METHOD">This study included all young people, aged 15 to 24, with an FEP who attended Orygen Youth Health in Melbourne, from a geographically defined catchment area encompassing Northern and Western Melbourne, over a 44-month period. Neighbourhood demographic data was collected from the 2011 Australian National Census. Negative binomial regression was used to determine incidence rate ratios controlled for age, sex and migrant status.</AbstractText>
<AbstractText Label="RESULTS">A total of 747 young people had an FEP during the 44-month study period and 722 were included in this study. Of these, 58.0% were males and 67.9% had a non-affective psychotic disorder; the mean age of the cohort was 19.1 years. The incidence of FEP in young people aged 15 to 24 in the catchment area was 123.2 per 100,000 person-years. There was a higher incidence of FEP in neighbourhoods of greatest social deprivation (IRR = 1.65, CI = 1.06-2.51, p = .02), highest unemployment (IRR = 1.56, CI = 1.04-2.35, p = .03) and above average social fragmentation (IRR = 1.42, CI = 1.02-1.97, p = .04), when controlled for age, sex and migrant status.</AbstractText>
<AbstractText Label="CONCLUSIONS">This study highlights variation in psychotic disorder incidence and the need for this disparity to be reflected in appropriate resource allocation.</AbstractText>
<CopyrightInformation>Copyright © 2019. Published by Elsevier B.V.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Eaton</LastName>
<ForeName>Scott</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Harrap</LastName>
<ForeName>Benjamin</ForeName>
<Initials>B</Initials>
<AffiliationInfo>
<Affiliation>Melbourne Epicentre, Melbourne Health and The University of Melbourne, 300 Grattan Street, Royal Melbourne Hospital, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Downey</LastName>
<ForeName>Linglee</ForeName>
<Initials>L</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Thien</LastName>
<ForeName>Kristen</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Bowtell</LastName>
<ForeName>Meghan</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Bardell-Williams</LastName>
<ForeName>Melissa</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ratheesh</LastName>
<ForeName>Aswin</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia; Orygen Youth Health, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>McGorry</LastName>
<ForeName>Patrick</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>O'Donoghue</LastName>
<ForeName>Brian</ForeName>
<Initials>B</Initials>
<AffiliationInfo>
<Affiliation>Orygen, The National Centre of Excellence in Youth Mental Health, 35 Poplar Road Parkville, Victoria 3052, Australia; Centre for Youth Mental Health, The University of Melbourne, 35 Poplar Road, Parkville, Victoria 3052, Australia; Orygen Youth Health, 35 Poplar Road, Parkville, Victoria 3052, Australia. Electronic address: brian.odonoghue@orygen.org.au.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic">
<Year>2019</Year>
<Month>05</Month>
<Day>24</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo>
<Country>Netherlands</Country>
<MedlineTA>Schizophr Res</MedlineTA>
<NlmUniqueID>8804207</NlmUniqueID>
<ISSNLinking>0920-9964</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D001315" MajorTopicYN="N" Type="Geographic">Australia</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002391" MajorTopicYN="N">Catchment Area, Health</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D061345" MajorTopicYN="N">Early Medical Intervention</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011618" MajorTopicYN="N">Psychotic Disorders</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012111" MajorTopicYN="N">Residence Characteristics</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012959" MajorTopicYN="Y">Socioeconomic Factors</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="Y">Incidence</Keyword>
<Keyword MajorTopicYN="Y">Neighbourhood</Keyword>
<Keyword MajorTopicYN="Y">Psychosis</Keyword>
<Keyword MajorTopicYN="Y">Psychotic disorder</Keyword>
<Keyword MajorTopicYN="Y">Schizophrenia</Keyword>
<Keyword MajorTopicYN="Y">Social deprivation</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="received">
<Year>2018</Year>
<Month>04</Month>
<Day>03</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised">
<Year>2019</Year>
<Month>03</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted">
<Year>2019</Year>
<Month>04</Month>
<Day>20</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed">
<Year>2019</Year>
<Month>5</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2020</Year>
<Month>8</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez">
<Year>2019</Year>
<Month>5</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList>
<ArticleId IdType="pubmed">31130401</ArticleId>
<ArticleId IdType="pii">S0920-9964(19)30142-2</ArticleId>
<ArticleId IdType="doi">10.1016/j.schres.2019.04.017</ArticleId>
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</pubmed>
<affiliations>
<list>
<country>
<li>Australie</li>
</country>
<region>
<li>Victoria (État)</li>
</region>
<settlement>
<li>Melbourne</li>
</settlement>
<orgName>
<li>Université de Melbourne</li>
</orgName>
</list>
<tree>
<country name="Australie">
<region name="Victoria (État)">
<name sortKey="Eaton, Scott" sort="Eaton, Scott" uniqKey="Eaton S" first="Scott" last="Eaton">Scott Eaton</name>
</region>
<name sortKey="Bardell Williams, Melissa" sort="Bardell Williams, Melissa" uniqKey="Bardell Williams M" first="Melissa" last="Bardell-Williams">Melissa Bardell-Williams</name>
<name sortKey="Bowtell, Meghan" sort="Bowtell, Meghan" uniqKey="Bowtell M" first="Meghan" last="Bowtell">Meghan Bowtell</name>
<name sortKey="Downey, Linglee" sort="Downey, Linglee" uniqKey="Downey L" first="Linglee" last="Downey">Linglee Downey</name>
<name sortKey="Harrap, Benjamin" sort="Harrap, Benjamin" uniqKey="Harrap B" first="Benjamin" last="Harrap">Benjamin Harrap</name>
<name sortKey="Mcgorry, Patrick" sort="Mcgorry, Patrick" uniqKey="Mcgorry P" first="Patrick" last="Mcgorry">Patrick Mcgorry</name>
<name sortKey="O Donoghue, Brian" sort="O Donoghue, Brian" uniqKey="O Donoghue B" first="Brian" last="O'Donoghue">Brian O'Donoghue</name>
<name sortKey="Ratheesh, Aswin" sort="Ratheesh, Aswin" uniqKey="Ratheesh A" first="Aswin" last="Ratheesh">Aswin Ratheesh</name>
<name sortKey="Thien, Kristen" sort="Thien, Kristen" uniqKey="Thien K" first="Kristen" last="Thien">Kristen Thien</name>
</country>
</tree>
</affiliations>
</record>

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